Medicinal plants, amalaki, Emblica officinalis, amla, research work

Research works by young scientists on Emblica Officinalis


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Research works by young scientists on Emblica Officinalis

Name: Kashifa Khanum
email: kashifakhanum@hotmail.com
qualification: B.Pharm
matter: Chemical composition / key active

constituents : Amla is highly nutritious and is an important dietary source of Vitamin C, minerals and amino acids. The edible fruit tissue contains protein concentration 3-fold and ascorbic acid concentration 160-fold compared to that of the apple. The fruit also contains considerably higher concentration of most minerals and amino acids than apples. Glutamic acid, proline, aspartic acid, alanine, and lysine are 29.6%, 14.6%, 8.1%, 5.4% and 5.3% respectively of the total amino acids. The pulpy portion of fruit, dried and freed from the nuts contains: gallic acid 1.32%, tannin, sugar 36.10%; gum 13.75%; albumin 13.08%; crude cellulose 17.08%; mineral matter 4.12% and moisture 3.83%. Amla fruit ash contains chromium, 2.5 ppm; zinc 4 ppm; and copper, 3 ppm.Key Active ConstituentsEmblicanin A&B, Puniglucanin, Pedunculagin, 2-keto-gluconolactone (Vitamin-C equivalents). Ellagic acid, Hexahydroxy-diphenic acid and conjugates.

Pharmacology:
Emblica officinalis is effective in the treatment of amlapitta [peptic ulcer]and in dyspepsia. The fruits exhibit hypolipiadaemic and antiatherosclerotic effects in rabbits & rats. The fruit extract has antimutagenic activity on certain directly acting mutagens in some strains of Salmonella typhimurium.The extract of amla also has antimicrobial properties. Amlaki is an antioxidant with free radical scavenging properties which may be due to the presence of high levels of super oxide dismutase.

 

 

References:
CAS, IP, Ayurveda book etc.
1 Chem Abstr, 1992 [116- 19982, 127273]; 1993 [119-103470]; 1989[110-73906];
Vohora, Indian Drugs, [1989-26(10), 526]; Janjua, Hamdard, 1991 [34(2)-104];
Yaqeenudin et. al., Pakist J Sci Ind Res, 1990 [33-268].
2 Roy, A.K. et. al., Int. J.of Pharmacog., 1991, v. 29(2), 117-126.
3 Mand, J.K. et. al., J. Res. Edu. in Ind.Med., 1991, v., 10(2), 1-7.
4 Ghosh, A. et. al., Int. J. of Pharmacog., 1993, v. 31(2), 116-120.
5 Mathur, R. et. al., J. of Ethnopharmacol., 1996, v., 50(2), 61-68.
6 Singh, B.N. and Sharma, P.V., J.Res. Ind. Med., 1971, 5, 223.
7 Ramaswamy, Minor Forest Products, Mysore, 1945,55; Damodaran & Nair,Biochem.J. 1936,30,1014;Giri,Indian J. med. Res., 1939, 27, 429; Mitra & Ghosh,Ann. biochem.1941, 1, 307; Srinivasan, loc. cit.
8 Chawla et. al., 1982, Indian J. Med. Res. 76 (Suppl.), 95-98.

Occupation: Pharmaceutical Industry
City: Karachi
Country: Pakistan


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